They graciously agreed to replace it and even set up shipping so that the new control box came on the same day I returned from vacation. I must have sent her 50 emails over the course of a month! In any case, between the two of us, we determined that the filter pump wasn't working in my control box. They were extremely patient with me and assisted me at every step. I had been in close contact with Rec unlimited the entire time. After about ten days, I emptied it and refilled it. It was cloudy no matter what I did, what chemicals I used, what filtration mode I had it on (regular, UVC, ozonator). The water wouldn't clear up after filling it. They shipped it from Indiana to Michigan. Written by Jackie Reimann, a Basketball Goal Specialist at Recreation Unlimited and the The Division Line: Line that marks the center of the court Diagram for an NBA Full Basketball Courtĭiagram for an International Full Basketball Courtĭiagram for a High School Basketball Court The Key: Also called the free throw lane or “the paint” is 16 feet wide for NBA and FIBA, and 12ft wide for College, High school and Junior High play and Extends 15’from the backboard to the free throw lineĬircles: There are three 6′ circles on a court, one in the center of the court and one on each end centered on the foul line. The Foul Line: For all Courts, The foul line distance is 15′ from the foul line to the front of the backboard and 18′ 10″ from the baseline. High school, and Junior High court 84 feet (26 m) by 50 feet (15 m).International Basketball the court 28 meters (92 ft) by 15 meters (49 ft).Professional NBA and College Basketball court is 94 feet (29 m) by 50 feet (15 m).
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Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) The planned study design may be modified in accordance with the adaptive features of the clinical study protocol. Additional cohorts may be enrolled to explore additional dose levels. Part A will have 6 cohorts and Part B will have 3. The remaining 6 subjects in a cohort will be randomized 4:2 AER-271:placebo and administered study drug after the SMB has reviewed the first 24 hours of safety data for the first 4 subjects. Part B sentinel dosing will randomize the first 4 subjects 2:2 AER-271:placebo. The remaining 6 subjects in a cohort will be randomized 5:1 AER-271:placebo and administered drug after the Safety Monitoring Board (SMB) has reviewed the first 24 hours of safety data for the first 2 subjects. Part A sentinel dosing will randomize the first 2 subjects 1:1 AER-271:placebo. Both Parts A and B will comprise an adaptive design. Top of Page Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More InformationĪ double-blind, randomized, placebo-controlled, sequential-group, single and multiple intravenous dose escalation study conducted in 2 parts. Data from this trial will also be used to develop a protocol for a subsequent Phase 2 clinical trial in stroke patients. An additional exploratory objective of this study is to evaluate the effects of AER-271 on electrocardiogram parameters including QT interval corrected for heart rate. Secondary objectives include: determining the pharmacokinetics of AER-271 and AER-270 following administration of AER-271, determining the dose proportionality for AER-270 and 271, and comparing the effects of continuous infusion versus multiple bolus doses on AER-271 exposure and adverse events. The primary objectives of this study are to assess the safety and tolerability of single and multiple IV doses and continuous infusion of AER-271 in healthy subjects. Both Parts A and B will follow an adaptive design including the use of Sentinel Dosing. The subsequent Part B is a multiple ascending dose, sequential group study. The study will be conducted in 2 parts: Part A is a single ascending dose, sequential group study. AER-271 is an Aquaporin-4 inhibitor designed to prevent brain swelling in severe ischemic stroke. This is a double-blind, randomized, placebo-controlled, sequential-group study to assess the safety, tolerability and pharmacokinetics of single ascending dose and multiple ascending doses of intravenously (IV) administered AER-271 in healthy human subjects.
There are a few ways to increase the likelihood of success though, like choosing the appropriate dwarf crayfish species, setting up your tank with both species in mind, having ideal water conditions, and making adjustments at the first signs of trouble. Even if things seem to be going well for an extended period of time, there is always the possibility that one day one of them may be missing from the tank. At the end of the day, compatibility is largely decided on by the personality of the fish and the crayfish. However, a considerable amount of hobbyists have had success keeping both betta and dwarf crayfish together in the same aquarium. Unfortunately, this is usually based on trial and error and ends up in a missing invertebrate or damaged betta. There is a lot of discussions about which tank mates can actually go with betta fish and which can’t. Keep reading to find out everything you need to know about keeping dwarf crayfish with betta fish together in your freshwater aquarium! Can dwarf crayfish live with a betta fish? There are a few extra steps you will need to take in order for your dwarf crayfish and betta fish to live peacefully together, but regular maintenance and upkeep is easy and very rewarding! While this is true for the most part, there have been some success stories with keeping bettas with small invertebrates, like dwarf crayfish. You might have heard that betta fish can’t be kept with anything else, at all. Freeze Your Foodįreezing your fresh food before it goes bad helps your wallet and the environment. This can quickly get out of hand and push you over budget. It’s also important you make sure you actually need the item you’re purchasing instead of buying it for the sale. While a single coupon might not give you a large discount, you can save a lot with multiple coupons. These usually work in person or online, so you can shop when and how you like. Be sure to download and register your email for new updates and sales. Many popular grocery stores are rolling out apps that track your coupons and savings. Cut CouponsĬoupons are easy to find in the mail, in store, in your inbox, and even in a Google search. Trimming your food budget can help you stow away more for your financial goals, such as building an emergency fund or saving for a dream vacation. There are several ways to cut back on what you spend without sacrificing the quality and taste of your food. With a little practice, she’ll better learn her habits and be able to accurately adjust her budget. So she’ll need a total of $385 for food each month. She would budget six percent for groceries ($210) and five percent for restaurants ($175). For example, Rita makes $3,500 per month after taxes. With this framework in mind, you can calculate your total food budget based on your take-home income. Approximately six percent is spent on groceries, while five percent is spent dining out - including dates, lunches with coworkers, and Sunday brunch. It doesn’t all go towards groceries, though. Department of Agriculture, Americans spend 11 percent of their take-home income on food. Dining Outĭon’t forget what you spend at restaurants when you consider your food budget. Go to Mint coach Purchasing Groceries vs. To overcome this problem, an ontology of experimental procedures can be interrogated to provide a most likely candidate for the missing semantic role(s). Occasionally, the text does not contain fillers for all of the semantic role slots that are needed to perform an adequate analysis of a verb. Using the observation that the structure of scholarly writing in the laboratory-based experimental sciences closely follows the laboratory procedures, we focus on the procedural verbs in the Methods section. One goal is to provide FrameNet and VerbNet-like ontologies for the specialized domain of biochemistry. Based on a descriptive taxonomy of rhetorical moves structured around IMRaD, the foundational linguistic knowledge needed for a computationally feasible model of the rhetorical moves is described: semantic roles. One subtask in identifying the argumentation structure is the identification of rhetorical moves, text segments that are rhetorical and perform specific communicative goals, in the Methods section. Argumentation mining can be used to validate scientific claims and experimental methodology, and to plot deeper chains of scientific reasoning. Recently, a new challenging information extraction task has been introduced as a means of obtaining these types of detailed information: identifying the argumentation structure in biomedical articles. Many Biomedical Natural Language Processing tasks take advantage of this structure. Scholarly writing in the experimental biomedical sciences follows the IMRaD (Introduction, Methods, Results, and Discussion) structure. Growing old with a best friend is like having a lifelong partner in crime, someone who will always be there for you and have your back no matter what.Ģ1. Growing old with a best friend is like having a lifelong companion on life’s journey, always there to share in the pains and gains.Ģ0. Growing old with a best friend is like having a twin soul, someone who understands you on a deeper level and will always be there to support you.ġ9. The beauty of growing old with a best friend is that they become like family, always there to support and encourage you no matter what.ġ8. A true best friend is someone who will grow old with you and still make you laugh just as much as they did when you first met.ġ7. A best friend is someone who will grow old with you and still be just as excited to share new experiences and create new memories together.ġ6. Growing old with a best friend is like having a constant source of encouragement, someone who will always be there to support you in your dreams and aspirations.ġ5. Having a best friend is like having a partner in life, growing old together and creating a lifetime of memories that will last a lifetime.ġ4. Growing old with a best friend is like having a constant companion on life’s journey, always there to share in the joys and sorrows.ġ3. Having a best friend is like having a constant source of comfort and understanding, someone who will always be there to listen and support you as you grow old together.ġ2. A best friend is someone who will grow old with you and still be just as excited to share new experiences and make new memories together.ġ1. Growing old with a best friend is like having a lifetime supply of laughter and good times, never running out of things to talk about and always having a good time together.ġ0. Having a best friend is like having a life companion, growing old together and experiencing all the joys and challenges that come with it.ĩ. Growing old with a best friend is like having a constant source of love and support, someone who will always be there to lift you up when you need it.Ĩ. A best friend will grow old with you and still be just as excited to spend time with you as they were when you first met.ħ. Growing old with a best friend is like having a permanent companion on life’s journey, someone who will always have your back and be there to celebrate your successes.Ħ. The beauty of growing old with a best friend is that they become a part of your story, and you become a part of theirs.ĥ. A true best friend will be there for you through the good times and the bad, growing old together and creating a lifetime of memories.Ĥ. Growing old with a best friend is like watching a beautiful painting come to life, each stroke of the brush bringing new meaning and beauty to the picture.ģ. The best thing about having a best friend is growing old with someone who knows all your secrets and still loves you anyway.Ģ. Best Friends Growing Old Together Quotesġ. Get ready to feel all the feels and be reminded of the priceless bond you share with your best friend. Here’s a collection of the best friends growing old together quotes to inspire and warm your heart. Cherish these moments and celebrate the beauty of growing old together with your BFF. Do you ever think about what it would be like to grow old with your best friend by your side? The memories you’ve shared together, the laughs and tears, the milestones and adventures – they’re all part of what makes your friendship so special.Īs you look ahead to the future, imagine the comfort and support that comes with having a best friend by your side through life’s journey. You can use networks like MSN, Yahoo!, Google Talk, Jabber, AOL Instant messenger, Gmail, Hotmail Messenger, Facebook chat and updates from social networks like Twitter, Myspace and Facebook, etc. Digsbyĭigsby is a free Windows instant messenger program client that puts IM, Email and social networks together. It has interoperability feature with AIM messenger, Yahoo, Facebook, GTalk and ICQ. You can send fun animations to other members in a chat room. Various room categories available like music, politics, sports, religion and many more. You can access thousands of live video chat rooms. It supports text chat, live chat and video call. Paltalk Messenger is a free instant messenger. Numerous plugins also extend Pidgin's functionality above and beyond the standard features. Pidgin supports file transfers, away messages, buddy icons and typing notifications. It is compatible with the following chat networks out of the box: AIM, ICQ, Google Talk, Jabber/XMPP, MSN Messenger, Yahoo!, Bonjour, Novell GroupWise Messenger, etc. Pidgin is an IM chat program which lets you log into accounts on multiple chat networks simultaneously. You can also follow your friends, post photos and status messages to stay connected in real time. AOL Instant Messenger enables you to add a variety of accounts such as Facebook, Twitter, YouTube or chat with your friends on AIM messenger, Facebook and Google Talk. AIM (AOL Instant Messenger) AIM (AOL Instant Messenger) is a free messenger that connects you with your friends and family instantly. It also helps you to manage your social networks such as Facebook and Twitter. It has various features such as audio and video chat, file transfers, group chats, message history, avatars, multiple simultaneous connections to the same network, and encrypted messaging. This instant messenger for Windows supports chatting on Windows Live, Facebook, Yahoo, MySpace, AIM, Email, Google Talk, Skype etc. Its themes make it attractive with dozens of themes to suit your mood every day. Trillian is a free fully featured, stand-alone and one of the most popular standalone instant messenger. Click instant messaging to learn about the definition of instant messaging and how does instant messaging work. In the following article, we have collected 10 best instant messenger alternatives for you. The list is very big and every service provider has their own chat messenger application: Google has GTalk, Yahoo has Yahoo Messenger, Windows Live has Windows Live Messenger, etc. People have their contacts on different mail networks like Gmail, Yahoo, Windows Live, Facebook, AOL, etc. We know that Windows messengers are not as popular as mobile IM apps, but there are also some great ones. However, what if you are looking for an instant messenger for your Windows computer or Mac? As developers are getting crazy about instant messaging function for mobile devices, we can see so many IM apps provided for your Android/iPhone. The integration of instant messenger and popular online services has reduced the need for an IM client, especially when comes to a PC platform, but it hasn't vanished completely. 10 Best Instant Chat Messenger Alternatives for PC/Mac Hopdoddy Burger Bar has a new Birria Burger, their take on birria tacos, made with beef patties, house-made chorizo stacked on a grilled/crisp quesadilla, cilantro onion aioli, and a side of "consome" (does someone does not know how to spell consommé?) and a Churro Shake in collaboration with Siete Foods made with vanilla custard, cinnamon sugar, Siete churros, and whipped cream. Choices include Sonoma Greens Salad, Lobster Bisque, Iceberg Wedge Salad, Prime Meatballs with steak sauce, Broiled Salmon, Chicken Breast "Stroganoff", Filet Medallions, Steak Salad, Prime Burger with French fries, Vegan Pappardelle Bolognese with plant-based sausage ragu, Carrot Cake with cream cheese icing, or Chocolate Chip Cookies.ĭIVE Coastal Cuisine has specials for September: Baja Fish Tacos with pico de gallo and lime ranch Stone Fruit & Roasted Beet Salad with goat cheese tarragon spread and Roasted Tarragon Cabbage. Truluck's has launched a new 45-minute power lunch menu with three courses for $39, served at the Uptown Dallas location from 11 am-3 pm. The menu features appetizers, salads, sandwiches, seafood, half-pound burgers, steaks. Signature dishes include Gorgonzola Burger, Bacon Wrapped BBQ Prawns, Beer Battered Fish & Chips BBQ Pork & Kimchi Fried Rice, Fish Tacos, and Traditional Scotch Eggs. Since its launch in 2010, Thirsty Lion has opened 12 locations in Texas, Arizona, Colorado, and Oregon this is the fifth in DFW. Thirsty Lion Gastropub is opening at 5225 Belt Line Rd. It's available online, via an app, or at a temporary pop-up at the Commissary in downtown Dallas. La Boca is a new delivery-only gelato company founded by Dallas local Owen Carlson and Argentina native Martin Pereyra de Olazábal, offering a selection of classic Argentine and vegan gelato varieties, including Dulce de Leche, Banana Split, Strawberry Sorbet, and Mint Chip. Fossils from 20 million years ago include fragments attributed to Victoriapithecus, the earliest Old World monkey. In the early Miocene, about 22 million years ago, there were many species of arboreally adapted primitive catarrhines from East Africa the variety suggests a long history of prior diversification. See also: Human evolution Sumatran orangutan ( Pongo abelii) Twenty-nine countries have instituted research bans to protect great apes from any kind of scientific testing. ĭue to the close genetic relationship between humans and the other great apes, certain animal rights organizations, such as the Great Ape Project, argue that nonhuman great apes are persons and should be given basic human rights. Those ancestors of the family Hominidae had already speciated from the family Hylobatidae (the gibbons), perhaps 15 to 20 million years ago. The most recent common ancestor of all Hominidae lived roughly 14 million years ago, when the ancestors of the orangutans speciated from the ancestral line of the other three genera. Within the taxon Hominidae, a number of extant and known extinct, that is, fossil, genera are grouped with the humans, chimpanzees, and gorillas in the subfamily Homininae others with orangutans in the subfamily Ponginae (see classification graphic below). Usage still varies, however, and some scientists and laypersons still use "hominid" in the original restrictive sense the scholarly literature generally shows the traditional usage until the turn of the 21st century. The current meaning of "hominid" includes all the great apes including humans. The earlier restrictive meaning has now been largely assumed by the term hominin, which comprises all members of the human clade after the split from the chimpanzees ( Pan). However, by the 1990s humans, apes, and their ancestors were considered to be "hominids". The original meaning of "hominid" referred only to humans ( Homo) and their closest extinct relatives. Several revisions in classifying the great apes have caused the use of the term hominid to vary over time. The Hominidae ( / h ɒ ˈ m ɪ n ɪ d iː/), whose members are known as the great apes or hominids ( / ˈ h ɒ m ɪ n ɪ d z/), are a taxonomic family of primates that includes eight extant species in four genera: Pongo (the Bornean, Sumatran and Tapanuli orangutan) Gorilla (the eastern and western gorilla) Pan (the chimpanzee and the bonobo) and Homo, of which only modern humans ( Homo sapiens) remain. Same with Tabbies, their patterns can be seen from various cat breeds – being up to 75% white with orange and black patches as part of their patterns. Tabbies can also be identified by the “M” marking on their forehead, dark eyeliner around their eyes, and slimmer belly than the rest of their body.Ĭalicos, on the other hand, are known for their patches with a wide range of colors: orange, black, and white. The following are the most common fur patterns Tabbies have: Physical AppearanceĪlthough Tabbies have various coat patterns, most Tabbies have striped-design coat patterns. Differences Between Tabby and Calico Cats 1. The smaller portion of male calico cats is usually sterile. One thing interesting about Calicos is their population, which females dominate. This domestic cat is rather friendly and independent, thus an ideal pet choice for families. And the amazing thing about these variations is that they are never the same! Like a snowflake, each pattern will have a unique distinction. Like Tabbies, Calico cats comprise a vast array of cat breeds in a way that has many variations. One amazing trivia about Tabbies is that they are male-dominated, and female Tabbies are rare! 2. It is also said that Tabbies might have come from the Middle East or France due to their known silk. The tabby cat pattern is one of the most common patterns among cat breeds. The coat patterns of this “mini-me” of wild tigers with stunning stripes could be seen as well with other cat breeds. Since most of them lived outdoors, the coat was cultivated to be thick to keep out the elements and keep the cat warm.Separate from most cat owners’ ideas about tabby cats, this type of cat is not a cat breed. Since this cat was meant to work, it was bred to be hardy, healthy and strong. The American Shorthair cat was a working cat that was used to keep the rodent population under control. The British Shorthair was one of the parents of this breed, which was originally known as the Domestic Shorthair. The first recorded breeding of the American Shorthair took place around 1904. Cats fitting the description of the American Shorthair were probably not native to the United States until the time of Columbus. However, this breed was bred out of cats that probably originated in Europe. The American Shorthair is considered to be the shorthaired cat that is native to the United States. The American is an easy cat to care for and makes a wonderful, quiet companion. She is an affectionate cat, but also spends time just sleeping in the sun. The American Shorthair tolerates being left alone. Even this Shorthair cat can get knots in her coat if she isn't brushed regularly. Interactive play may be necessary to keep her in good shape and make certain that she gets adequate exercise.ĭaily brushing is important, especially during the change of seasons when her coat is thickening or thinning. She will find a toy or create one out of anything she finds if a cat toy is not available. The American will play when she wants to play. Despite the heavy boning and musculature of the cat, you want to make certain that she keeps a proper weight and does not get out of condition. The American Shorthair is a thick, muscular cat and her nutrition must be carefully controlled. She is a very good companion for single people. If she is in the mood to play, she will bring her parent a toy. While the American loves to play, she doesn't need hourly attention. The American is a loving cat and will attach herself to all members of the family. The American Shorthair is a very pleasant companion cat. The texture of her coat is relatively hard as it is meant as protection for her. The coat of the American Shorthair is thick and dense. Her coat becomes much longer and thicker during the winter. She looks like what she was originally meant to be, a cat to keep rodents out of the barn and the house. She has a broad chest, a muscular neck, strong jaws and a well-developed muzzle. All components of this cat should be well developed. The American Shorthair is a powerful cat. Her rounded, thick appearance makes you realize that she will be heavy when you pick her up. The American Shorthair is a medium-sized cat, but she is a very powerful one. She is heavily muscled and has heavy boning. |
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